Pericytes are multi-potent mesenchymal-like cells found in association with small blood vessel walls. They are important for angiogenesis, the structural integrity of the microvasculature, and blood flow regulation. However, they can also develop into malignant tumors.

Pericytes contribute to tissue repair. They differentiate into adipocytes during fat tissue injury, into chondroblasts and bone after bone injury, and into myoblasts in a model for muscle dystrophy. Pericytes have demonstrated the ability to differentiate into fibroblasts and phagocytes (macrophages). Zen-Bio, Inc. offers placenta-derived Pericytes produced at Zen-Bio's facility from normal human tissues. Each vial contains 500,000 viable cells.

Quality control tests are performed for each lot of Human Pericyte cells. The cells are characterized by their surface markers via flow cytometry. Population distributions are expressed as percentage positive are presented on the certificate of analysis for each lot of cells. The cells are assessed for viability and for flow cytometry analysis of pericyte cell surface markers chondroitin sulfate proteoglycan 4 (NG2), CD140b molecule (the beta chain of the platelet derived growth factor receptor (PDGFr)), and CD13. Data are reported as a percentage (%) of the population.

These are phenotypic markers currently used to identify Pericytes. These cells have a guaranteed purity of 80% and a viability of 90%. In addition, all blood products have been tested for some common blood borne pathogens HIV-1, HIV-2, Hepatitis B, and Hepatitis C using US Food and Drug Administration (FDA) licensed testing procedures.

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